The full text of relevant articles was read and critiqued. If you are taking any other medicines. Ques : Can I take Dapoxetine with sildenafil? While FDB Multilex use reputable sources of information, such as published data of pharmaceutical manufacturers, it does not validate or verify the information received from third parties. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.About Dapoxetine. This medication is used to treat male sexual dysfunction such as premature ejaculation. It also acts as an antidepressant drug. The effectiveness of the drug will not be immediately visible. The results can be observed gradually over a . Dapoxetine, marketed as Priligy, among others, is a medication used for the treatment of premature ejaculation (PE) in men 18–64 years old. [3] [4] [5] Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin’s action at the postsynaptic cleft, and as a consequence promoting ejaculatory delay. [6]. Common or very common. Anxiety; asthenia; concentration impaired; constipation; diarrhoea; dizziness; drowsiness; dry mouth; gastrointestinal discomfort; gastrointestinal disorders; headache; hypotension; mood altered; nausea; paraesthesia; sexual dysfunction; sinus congestion; sleep disorders; sweat changes; syncope; tinnitus; tremor.